Product Evidence
We value your trust, and we want you to understand the research and rationale behind our products and their ingredients.
The following is an overview of the ingredients in Wave Bye products and the research behind those ingredients. This evidence has guided our product development and our claims around their potential effectiveness for period symptoms.
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Peer Reviewed Articles on Ingredients in Wave Bye's Product
Bye Irregularity
Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials
Authors: Dorina Greff, Anna E Juhász, Szilárd Váncsa, Alex Váradi, Zoltán Sipos, Julia Szinte, Sunjune Park, Péter Hegyi, Péter Nyirády, Nándor Ács, Szabolcs Várbíró, Eszter M Horváth
Excerpt: "Inositol is an effective and safe treatment in PCOS. Moreover, inositols showed non-inferiority in most outcomes compared to the gold standard treatment; metformin."
Magnesium prophylaxis of menstrual migraine: effects on intracellular magnesium
Author(s): F Facchinetti, G Sances, P Borella, A R Genazzani, G Nappi
Excerpt: "These data point to magnesium supplementation as a further means for menstrual migraine prophylaxis, and support the possibility that a lower migraine threshold could be related to magnesium deficiency."
The effects of oral ferrous bisglycinate supplementation on hemoglobin and ferritin concentrations in adults and children: a systematic review and meta-analysis of randomized controlled trials
Authors: Jordie A J Fischer, Arlin M Cherian, Jeffrey N Bone, Crystal D Karakochuk
Excerpt: "Ferrous bisglycinate shows some benefit over other iron supplements in increasing hemoglobin concentration and reducing GI adverse events among pregnant women."
Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials
Authors: M Diana van Die, Henry G Burger, Helena J Teede, Kerry M Bone
Excerpt: "Despite some methodological limitations, the results from randomised, controlled trials to date suggest benefits for Vitex extracts in the treatment of premenstrual syndrome, premenstrual dysphoric disorder and latent hyperprolactinaemia."
Bye Cramps
A Randomised Placebo-Controlled Trial To Determine The Effect Of Vitamin E In Treatment Of Primary Dysmenorrhoea
Authors: S Ziaei, S Faghihzadeh, F Sohrabvand, M Lamyian, T Emamgholy
Excerpt: "Both placebo and vitamin E are effective in relieving symptoms due to primary dysmenorrhoea, but the effects of vitamin E are more marked."